Endocrine Abstracts

Introduction: Cushing’s disease (CD) is a condition due to an ACTH-secreting pituitary adenoma and leading to hypercorticism. Hirsutism is common in CD but its exact frequency has been poorly studied. It results from the stimulating effect of ACTH on adrenal production of androgens.The aim of this study is to determine the androgenic profile in hirsute patients with CD.Patients and methods: It is a retrospective study of nine ...

Sleep apnoea syndrome (SAS) is common in acromegaly and both diseases are independently associated with hypertension and insulin resistance contributing to increased morbidity and mortality.The aim of this study was to assess the prevalence and risk factors of SAS in acromegaly, to study clinical and polysomnographic particularities of SAS in acromegaly and to analyze the effects of acromegaly treatment on SAS.It’s a retrospec...

Introduction: Cushing disease (CD) is a condition due to an ACTH-secreting pituitary adenoma that is usually a microadenoma. Seldom, the lesion may be atypical by his size or his radiological aspect.The aim of this study is to analyze the clinical and biological data of CD with atypical radiological aspect (macroadenoma or other), to compare them to those of CD with a typical radiological aspect (microadenoma) and to determine the clinical or biological ...

Pituitary enlargement with long standing hypothyroidism is well established.The clinical evolution of pituitary hyperplasia to thyroid hormone should be monitored closely during primary hypothyroidism because of the rare possibility of an incidental non thyrotropic pituitary tumor that will not regress on thyroid hormone. We report a case of a pituitary mass not responding to thyroid hormone therapy.A 46 years old women was admitte...

Most macroprolactinomas are responsive to dopamine against drugs. Bromocriptine (BRC) has been available and extensively used in our country. The aims are to assess the outcome in 29 patients with macroprolactinomas who were treated with BRC.Material and methods: A multicentric study of 29 patients with macroprolactinoma (19 female; 10 males). The mean age was 33 years. The pituitary mass was larger than 10 mm in diameter. There was no endocrinological e...

Introduction: Latent autoimmune diabetes in adults (LADA) is a genetically linked, autoimmune form of type 1 diabetes mellitus (DM) that accounts for 2–12% of all cases of diabetes.The goal of our study is to detect LADA among patients who were diagnosed as type 2 DM and who became insulin requiring.Methods: Our study included 45 patients (15 men, 30 women) diagnosed as type 2 DM, who had a poor glycemic control on oral hypogl...

Aims: Waist circumference is a convenient measure of abdominal adipose tissue,it correlates closely with BMI and is strongly linked to obesity- related risk factors. The sex specific waist circumference currently proposed for European male is 94 centimetres and for females is 80 cm. Thus, there is a need to develop sex specific waist circumference cut-offs points appropriate for different population (W.H.O).The aims are to determine the appropriate waist...